What is Lyophilization?
Lyophilization is to cool down the material containing a large amount of water in advance, freeze it into a solid, and then sublime the solid water directly under vacuum conditions, while the material itself remains in the ice shelf when frozen, so it remains in the same volume after drying. When solid water sublimates, it absorbs heat, causing the product temperature to drop, thereby slowing down the sublimation rate. In order to increase the sublimation rate and shorten the drying time, the product must be properly heated.
Lyophilization is carried out at low temperature, so it is particularly suitable for many heat-sensitive substances.
After the reagent is lyophilized, 95% of the water is removed, and proteins and microorganisms will not be denatured or lose their biological activity. The lyophilized product can be stored at room temperature without deterioration, so lyophilization technology is widely used in medical industry.
Why choose it?
The ordinary PCR 8-strip tube caps cannot be placed vertically on the 8-strip tubes before freeze drying. Therefore, the lyophilized 8-strip tubes can only be moved outside the freeze dryer and covered manually. Since the nitrogen in the tubes is lighter than air, air will enter the tube again, making the lyophilized reagent susceptible to moisture and oxidation, which will greatly shorten the effective storage time. In contrast, our company's lyophilized caps can be automatically operated in the freeze dryer. This not only saves manpower and time, but also reduces pollution and effectively preserves lyophilized reagents. In order to ensure that the PCR tube is not deformed by pressure during hydraulic sealing, we have limited the type of it and equipped it with a corresponding tube holder.
The lyophilized 8-strip tubes provided by our company can be used for freeze drying of all PCR amplification reagents, including forensic STR reagents and clinical qPCR reagents.
Post time: Feb-25-2025